US clinical study seeks to see if stem cells can cure baldness

Four American surgeons are the latest group of many worldwide who are attempting to see how stem cells could be used to combat baldness.

In the five-patient study lead by Kenneth Williams, D.O. of Orange County Hair Restoration, a clinical trial is taking place in which PRP and stem cells are being used in conjunction with each other to treat hair loss. Fat is removed from the abdomen before being emulsified to separate the stem cells. These cells are then mixed with the patient’s concentrated plasma before the mixed formula is injected into the scalp. Williams hopes the results of his study will be publishable in two years’ time. “The study is taking cells that are in our body that help to regenerate or stimulate inactive or dormant hair follicles,” he told news outlets. “That is the theory behind what we’re doing this procedure on.”

Overseas trials already showing promise

The American Hair Loss Association notes that two-thirds of men will experience some thinning by the age of 35, while by the age of 50, roughly 85 per cent will be affected by significant thinning.

It’s perhaps no wonder then that so many scientists around the world are searching for ways to utilise stem cells to cure the condition. Clinical trials in Japan for example are already making significant strides in research; Kyocera Corp and Organ Technologies are conducting regenerative medicine trials in attempts to develop a cure. Led by Takashi Tsuji, the research team has already had some success in regeneration using stem cells, using them to reinvigorate hair follicles in mice. Hormones can impact the natural cycle of hair follicle regeneration, which is powered by stem cells, as can damage caused via trauma. Taking tips from skin restoration, follicular regenerative medicine works by removing small patches of skin and hair follicles from scalp to extract active stem cells. These are then multiplied, processed, and transformed into follicles using what Tsuji has dubbed the primordium method. These transformed cells are then injected into the patient’s scalp. This process differs from current baldness cures as the hair follicles are actually regenerated, as opposed to treatments such as hair transplants, which simply move the hair from one place to another.

Given that approximately 18 million people suffer with hair loss in Japan, it’s not only Takashi Tsuji and his team who are on working on potential cures. Cosmetic giants Shiseido Co. have plans to release a cure for baldness throughout Japan and other countries in Asia as early as next year.

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